Shall I do it?
N is for Nagash the Black, the Usurper, the Warhammer Father of Necromancy

O for Ophelia from Romeo x Juliet or the former number 4 claymore in Claymore. :P

I had to go there. Also got one for Q when it comes up.

P is for Pericles, the Athenian Statesman.

Wait...that's a real character...nuts...

P is for Pandy (Pandora) from Hex Coda

Q is for Quatre Raberba Winner from Mobile Suit Gundam Wing. :P

R is for Riful, an awakened being from Claymore.

GUNDAM WING!!!!

S is for Silverbolt from Transformers: Beast Wars

T is for Toya/Tooya from Ceres, Celestial Legend

I had a T from Gundam Wing and another show but I'll save them. XD Nice to see someone else knows characters from Claymore, Riful is also the known as the witch of the west in the manga, not sure about the Anime since I haven't gotten that far into it yet.

U is for Utena from Revolutionary Girl Utena.

I've seen the series, and the movie, and read the manga.

V is for Vapula, a tomb-raider-esq purple-haired monster raiser and rare item collector

W is for Wash from Firefly.

Xiuhcoatl - The Aztec fire-snake who was the personification of drought and scorched earth.

Yuber - Suikoden 3

Z is for Zoey/Zoe from Digimon Frontier.

A is for Altaïr from Assassin's Creed.

B is for Brawn from Transformers.

C is for Casavir, a rogue Paladin on a quest to martyr himself fighting off monsters
(NWN 2)